ALDH1L1 anticorps (AA 282-424)
Aperçu rapide pour ALDH1L1 anticorps (AA 282-424) (ABIN7601093)
Antigène
Voir toutes ALDH1L1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 282-424
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Fonction
- Anti-ALDH1L1 Antibody Picoband®
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-ALDH1L1 Antibody Picoband® (ABIN7601093). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human ALDH1L1 recombinant protein (Position: N282-L424).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Champion, K. M., Cook, R. J., Tollaksen, S. L., Giometti, C. S. Identification of a heritable deficiency of the folate-dependent enzyme 10-formyltetrahydrofolate dehydrogenase in mice. Proc. Nat. Acad. Sci. 91: 11338-11342, 1994. 2. Gross, M. B. Personal Communication. Baltimore, Md. 11/2/2010. 3. Hong, M., Lee, Y., Kim, J. W., Lim, J. S., Chang, S. Y., Lee, K. S., Paik, S. G., Choe, I. S. Isolation and characterization of cDNA clone for human liver 10-formyltetrahydrofolate dehydrogenase. Biochem. Molec. Biol. Int. 47: 407-415, 1999. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))
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Autre désignation
- ALDH1L1
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Sujet
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Synonyms: Type I iodothyronine deiodinase, 5DI, DIOI, Type 1 DI, Type-I 5'-deiodinase, DIO1, ITDI1, TXDI1
Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.
Background: 10-formyltetrahydrofolate dehydrogenase is an enzyme that in humans is encoded by the ALDH1L1 gene. The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.
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Poids moléculaire
- 97 kDa
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ID gène
- 10840
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UniProt
- O75891
Antigène
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