CD79b anticorps (AA 29-229)

N° du produit ABIN7601115

Cet anticorps Souris Monoclonal détecte spécifiquement CD79b dans WB et IHC. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour CD79b anticorps (AA 29-229) (ABIN7601115)

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD79b est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 6H11

Détail du produit anti-CD79b anticorps

Épitope: AA 29-229

Fonction: Anti-CD79b Antibody Picoband®(monoclonal, 6H11)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CD79b Antibody Picoband® (monoclonal, 6H11) (ABIN7601115). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CD79b recombinant protein (Position: A29-E229). Human CD79b shares 70% amino acid (aa) sequence identity with mouse CD79b.

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
1. "Entrez Gene: CD79B CD79b molecule, immunoglobulin-associated beta" 2. Dobbs, A. K., Yang, T., Farmer, D., Kager, L., Parolini, O., Conley, M. E. Cutting edge: a hypomorphic mutation in Ig-beta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development. J. Immun. 179: 2055-2059, 2007. 3. Wood, W. J., Jr., Thompson, A. A., Korenberg, J., Chen, X., May, W., Wall, R., Denny, C. T. Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB). Genomics 16: 187-192, 1993.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CD79b

Antigène: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Autre désignation: CD79B

Sujet:

Synonyms: B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, CD79B, B29, IGB

Tissue Specificity: Expressed in colon, placenta, liver and very weakly in exocervix. Increased expression observed in lymph nodes of breast carcinoma.

Background: CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene. By fluorescence in situ hybridization, It is mapped to 17q23.3. The CD79B protein together with the related CD79A protein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also can enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Poids moléculaire: 35 kDa

ID gène: 974

UniProt: P40259

Pathways: BCR Signaling