DBF4 anticorps (AA 295-665)
Aperçu rapide pour DBF4 anticorps (AA 295-665) (ABIN7601162)
Antigène
Voir toutes DBF4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 295-665
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Fonction
- Anti-DBF4 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-DBF4 Antibody. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human DBF4 recombinant protein (Position:Y295-S665).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- DBF4 (DBF4 Homolog (DBF4))
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Autre désignation
- DBF4
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Sujet
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Background: Using both gain- and loss-of-function experiments, it was found that Xenopus Dbf4 inhibited canonical Wnt signaling. Depletion of endogenous Dbf4 did not disturb gastrulation movements or early organizer genes, but resulted in embryos with morphologically defective heart and eyes and suppressed cardiac markers. The function of Dbf4 in heart development appeared to be independent of its role in the cell cycle. Dbf4 interacted physically and functionally with Frodo, a context-dependent regulator of Wnt signaling.
Gene Full Name: DBF4-CDC7 kinase regulatory subunit
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Poids moléculaire
- 80 kDa
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ID gène
- 10926
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UniProt
- Q9UBU7
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication
Antigène
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