SRR anticorps (AA 3-283)

N° du produit ABIN7601183

Cet anticorps anti-SRR est un anticorps Lapin Polyclonal détectant SRR dans WB, IHC, ELISA, FACS, IF, IP et ICC. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour SRR anticorps (AA 3-283) (ABIN7601183)

Antigène: SRR (Serine Racemase (SRR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SRR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Détail du produit anti-SRR anticorps

Épitope: AA 3-283

Fonction: Anti-Serine racemase/SRR Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Serine racemase/SRR Antibody Picoband® (ABIN7601183). Tested in ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Serine racemase/SRR recombinant protein (Position: A3-E283).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. De Miranda, J., Santoro, A., Engelender, S., Wolosker, H. Human serine racemase: molecular cloning, genomic organization and functional analysis. Gene 256: 183-188, 2000. 2. Henneberger, C., Papouin, T., Oliet, S. H. R., Rusakov, D. A. Long-term potentiation depends on release of D-serine from astrocytes. Nature 463: 232-236, 2010. 3. Labrie, V., Fukumura, R., Rastogi, A., Fick, L. J., Wang, W., Boutros, P. C., Kennedy, J. L., Semeralul, M. O., Lee, F. H., Baker, G. B., Belsham, D. D., Barger, S. W., Gondo, Y., Wong, A. H. C., Roder, J. C. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model. Hum. Molec. Genet. 18: 3227-3243, 2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SRR

Antigène: SRR (Serine Racemase (SRR))

Autre désignation: SRR

Sujet:

Synonyms: Dermatopontin, Tyrosine-rich acidic matrix protein, TRAMP, DPT

Tissue Specificity: Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fibroblasts from patients with systemic sclerosis than in normal skin fibroblasts.

Background: SRR(serine racemase) is a 37 kDa protein and belongs to the serine/threonine dehydratase family. It plays a role in neuronal activity and a potential biological role in the regulation of N-methyl-D-aspartate (NMDA) receptor activity in these peripheral organs as well. SRR catalyzes the racemization between l- and d-serine.

Poids moléculaire: 37 kDa

ID gène: 63826