Fibulin 1 anticorps (AA 30-703)
Aperçu rapide pour Fibulin 1 anticorps (AA 30-703) (ABIN7601231)
Antigène
Voir toutes Fibulin 1 (FBLN1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 30-703
-
Fonction
- Anti-Fibulin 1/FBLN1 Antibody Picoband®
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins
-
Attributs du produit
- Anti-Fibulin 1/FBLN1 Antibody Picoband® (ABIN7601231). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- E.coli-derived human Fibulin 1/FBLN1 recombinant protein (Position: D30-F703).
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Argraves, W. S., Dickerson, K., Burgess, W. H., Ruoslahti, E. Fibulin, a novel protein that interacts with the fibronectin receptor-beta subunit cytoplasmic domain. Cell 58: 623-629, 1989. 2. Argraves, W. S., Tran, H., Burgess, W. H., Dickerson, K. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J. Cell Biol. 111: 3155-3164, 1990. 3. Bohlega, S., Al-Ajlan, H., Al-Saif, A. Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues. Europ. J. Hum. Genet. 22: 640-643, 2014. -
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Fibulin 1 (FBLN1)
-
Autre désignation
- FBLN1
-
Sujet
-
Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,
Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Background: FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.
-
Poids moléculaire
- 90 kDa
-
ID gène
- 2192
-
UniProt
- P23142
Antigène
-