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OPTC anticorps (AA 32-250)

Cet anticorps anti-OPTC est un anticorps Lapin Polyclonal détectant OPTC dans WB et ELISA. Adapté pour Humain et Singe.
N° du produit ABIN7601300

Aperçu rapide pour OPTC anticorps (AA 32-250) (ABIN7601300)

Antigène

Voir toutes OPTC Anticorps
OPTC (Opticin (OPTC))

Reactivité

  • 21
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Singe

Hôte

  • 19
  • 1
  • 1
Lapin

Clonalité

  • 19
  • 2
Polyclonal

Conjugué

  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Cet anticorp OPTC est non-conjugé

Application

  • 11
  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 2
Western Blotting (WB), ELISA
  • Épitope

    • 11
    • 3
    • 1
    • 1
    • 1
    AA 32-250

    Fonction

    Anti-OPTC Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-OPTC Antibody Picoband® (ABIN7601300). Tested in ELISA, WB applications. This antibody reacts with Human, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human OPTC recombinant protein (Position: E32-Q250).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human, Monkey
    ELISA, 0.1-0.5 μg/mL, -
    1. Friedman, J. S., Faucher, M., Hiscott, P., Biron, V. L., Malenfant, M., Turcotte, P., Raymond, V., Walter, M. A. Protein localization in the human eye and genetic screen of opticin. Hum. Molec. Genet. 11: 1333-1342, 2002. 2. Reardon, A. J., Le Goff, M., Briggs, M. D., McLeod, D., Sheehan, J. K., Thornton, D. J., Bishop, P. N. Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix. J. Biol. Chem. 275: 2123-2129, 2000.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    OPTC (Opticin (OPTC))

    Autre désignation

    OPTC

    Sujet

    Synonyms: One cut domain family member 2, Hepatocyte nuclear factor 6-beta, HNF-6-beta, One cut homeobox 2, Transcription factor ONECUT-2, OC-2, ONECUT2, HNF6B

    Tissue Specificity: Predominantly expressed in testis and placenta as well as in many cell lines, including epithelial cell lines.

    Background: Opticin is a protein that in humans is encoded by the OPTC gene. Opticin belongs to class III of the small leucine-rich repeat protein (SLRP) family. Members of this family are typically associated with the extracellular matrix. Opticin is present in significant quantities in the vitreous of the eye and also localizes to the cornea, iris, ciliary body, optic nerve, choroid, retina, and fetal liver. Opticin may noncovalently bind collagen fibrils and regulate fibril morphology, spacing, and organization. The opticin gene is mapped to a region of chromosome 1 that is associated with the inherited eye diseases age-related macular degeneration (AMD) and posterior column ataxia with retinosa pigmentosa (AXPC1).

    Poids moléculaire

    37 kDa

    ID gène

    26254
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