JDP2 anticorps (AA 33-163)

N° du produit ABIN7601338

L’anticorps Lapin Polyclonal anti-JDP2 a été validé pour WB et ELISA. Il convient pour détecter JDP2 dans des échantillons de Humain.

Aperçu rapide pour JDP2 anticorps (AA 33-163) (ABIN7601338)

Antigène: JDP2 (Jun Dimerization Protein 2 (JDP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JDP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-JDP2 anticorps

Épitope: AA 33-163

Fonction: Anti-JDP2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-JDP2 Antibody Picoband® (ABIN7601338). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human JDP2 recombinant protein (Position: E33-K163).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 7/23/2013. 2. Heinrich, R., Livne, E., Ben-Izhak, O., Aronheim, A. The c-Jun dimerization protein 2 inhibits cell transformation and acts as a tumor suppressor gene. J. Biol. Chem. 279: 5708-5715, 2004. 3. Ji, H., Ehrlich, L. I. R., Seita, J., Murakami, P., Doi, A., Lindau, P., Lee, H., Aryee, M. J., Irizarry, R. A., Kim, K., Rossi, D. J., Inlay, M. A., Serwold, T., Karsunky, H., Ho, L., Daley, G. Q., Weissman, I. L., Feinberg, A. P. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 467: 338-342, 2010.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur JDP2

Antigène: JDP2 (Jun Dimerization Protein 2 (JDP2))

Autre désignation: JDP2

Sujet:

Synonyms: Relaxin receptor 2, G-protein coupled receptor 106, G-protein coupled receptor affecting testicular descent, Leucine-rich repeat-containing G-protein coupled receptor 8, Relaxin family peptide receptor 2, RXFP2, GPR106, GREAT, LGR8

Tissue Specificity: Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.

Background: Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. Mouse Jdp2 is an inhibitory subunit of the differentiation regulatory factor (DRF) complex. Jdp2 repressed retinoic acid-induced transcription of the Jun gene by recruiting a histone deacetylase-3 -containing complex to the differentiation response element (DRE) of the Jun promoter. Expression of JDP2 was reduced in several human cancers compared with matched normal tissues. Human JDP2 has antitumorigenic properties.

Poids moléculaire: 19 kDa

ID gène: 122953

Pathways: Chromatin Binding