RBP3 anticorps (AA 333-1196)

N° du produit ABIN7601363

Cet anticorps anti-RBP3 est un anticorps Lapin Polyclonal détectant RBP3 dans WB, ELISA et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour RBP3 anticorps (AA 333-1196) (ABIN7601363)

Antigène: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBP3 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-RBP3 anticorps

Épitope: AA 333-1196

Fonction: Anti-IRBP/RBP3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-IRBP/RBP3 Antibody Picoband® (ABIN7601363). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human IRBP/RBP3 recombinant protein (Position: L333-R1196).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Carson, N. L., Simpson, N. E. A physical map of 13 markers on chromosome 10 from dosage studies on abnormal cell lines. (Abstract) Cytogenet. Cell Genet. 51: 974-975, 1989. 2. Chin, K. S., Mathew, C. G. P., Fong, S. L., Bridges, C. D. B., Ponder, B. A. J. Styl RFLP recognised by a human IRBP cDNA localised to chromosome 10. Nucleic Acids Res. 16: 1645 only, 1988. 3. Danciger, M., Kozak, C. A., Nickerson, J., Redmond, T. M., Farber, D. B. Localization of the gene for interphotoreceptor retinoid-binding protein to mouse chromosome 14 near Np-1. Genomics 8: 727-731, 1990.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur RBP3

Antigène: RBP3 (Retinol Binding Protein 3, Interstitial (RBP3))

Autre désignation: RBP3

Sujet:

Synonyms: Ras-related protein Rab-6A, Rab-6, RAB6A, RAB6

Tissue Specificity: Ubiquitous.

Background: Retinol-binding protein 3, interstitial (RBP3), also known as IRBP is a protein that in humans is encoded by the RBP3 gene. Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38 % identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively.

Poids moléculaire: 135 kDa

ID gène: 5949

UniProt: P10745