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ZW10 anticorps (AA 35-779)

L’anticorps Lapin Polyclonal anti-ZW10 a été validé pour WB, ELISA et FACS. Il convient pour détecter ZW10 dans des échantillons de Humain.
N° du produit ABIN7601437

Aperçu rapide pour ZW10 anticorps (AA 35-779) (ABIN7601437)

Antigène

Voir toutes ZW10 Anticorps
ZW10 (Zw10 Kinetochore Protein (ZW10))

Reactivité

  • 39
  • 28
  • 19
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 33
  • 6
Lapin

Clonalité

  • 34
  • 5
Polyclonal

Conjugué

  • 20
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp ZW10 est non-conjugé

Application

  • 23
  • 13
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Épitope

    • 9
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-779

    Fonction

    Anti-ZW10 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-ZW10 Antibody Picoband® (ABIN7601437). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human ZW10 recombinant protein (Position: K35-K779).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x10^6 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chan, G. K. T., Jablonski, S. A., Starr, D. A., Goldberg, M. L., Yen, T. J. Human Zw10 and ROD are mitotic checkpoint proteins that bind to kinetochores. Nature Cell Biol. 2: 944-947, 2000. 2. Musio, A., Mariani, T., Montagna, C., Zambroni, D., Ascoli, C., Ried, T., Vezzoni, P. Recapitulation of the Roberts syndrome cellular phenotype by inhibition of INCENP, ZWINT-1 and ZW10 genes. Gene 331: 33-40, 2004. 3. Scaerou, F., Starr, D. A., Piano, F., Papoulas, O., Karess, R. E., Goldberg, M. L. The ZW10 and rough deal checkpoint proteins function together in a large, evolutionarily conserved complex targeted to the kinetochore. J. Cell Sci. 114: 3103-3114, 2001.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    ZW10 (Zw10 Kinetochore Protein (ZW10))

    Autre désignation

    ZW10

    Sujet

    Synonyms: Calretinin, CR, 29 kDa calbindin, CALB2, CAB29

    Tissue Specificity: Brain.

    Background: Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis.

    Poids moléculaire

    95 kDa

    ID gène

    9183

    UniProt

    O43264
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