TRPS1 anticorps (AA 353-1257)

N° du produit ABIN7601443

L’anticorps Lapin Polyclonal anti-TRPS1 a été validé pour WB, IHC, ELISA, IF, FACS et ICC. Il convient pour détecter TRPS1 dans des échantillons de Humain.

Aperçu rapide pour TRPS1 anticorps (AA 353-1257) (ABIN7601443)

Antigène: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPS1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-TRPS1 anticorps

Épitope: AA 353-1257

Fonction: Anti-TRPS1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TRPS1 Antibody Picoband® (ABIN7601443). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TRPS1 recombinant protein (Position: H353-D1257).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Balducci, R., Toscano, V., Tedeschi, B., Mangiantini, A., Toscano, R., Galasso, C., Cianfarani, S., Boscherini, B. A new case of Ambras syndrome associated with a paracentric inversion(8)(q12,q22). Clin. Genet. 53: 466-468, 1998. 2. Baumeister, F. A. M., Egger, J., Schildhauer, M. T., Stengel-Rutkowski, S. Ambras syndrome: delineation of a unique hypertrichosis universalis congenita and association with a balanced pericentric inversion (8)(p11.2,q22). Clin. Genet. 44: 121-128, 1993. 3. Fantauzzo, K. A., Kurban, M., Levy, B., Christiano, A. M. Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 8: e1003002, 2012. Note: Electronic Article.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TRPS1

Antigène: TRPS1 (Trichorhinophalangeal Syndrome I (TRPS1))

Autre désignation: TRPS1

Sujet:

Synonyms: Mannan-binding lectin serine protease 2, MBL-associated serine protease 2, Mannose-binding protein-associated serine protease 2, MASP-2, MASP2

Tissue Specificity: Plasma.

Background: Zinc finger transcription factor Trps1 is a protein that in humans is encoded by the TRPS1 gene. This gene encodes a transcription factor that represses GATA-regulated genes and binds to a dynein light chain protein. Binding of the encoded protein to the dynein light chain protein affects binding to GATA consensus sequences and suppresses its transcriptional activity. Defects in this gene are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III.

Poids moléculaire: 150 kDa

ID gène: 7227

Pathways: Protein targeting to Nucleus