TMEM59 anticorps (AA 37-323)

N° du produit ABIN7601499

Cet anticorps Lapin Polyclonal détecte spécifiquement TMEM59 dans WB, ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour TMEM59 anticorps (AA 37-323) (ABIN7601499)

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-TMEM59 anticorps

Épitope: AA 37-323

Fonction: Anti-TMEM59 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-TMEM59 Antibody Picoband® (ABIN7601499). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TMEM59 recombinant protein (Position: A37-I323).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Boada-Romero, E., Letek, M., Fleischer, A., Pallauf, K., Ramon-Barros, C., Pimentel-Muinos, F. X. TMEM59 defines a novel ATG16L1-binding motif that promotes local activation of LC3. EMBO J. 32: 566-582, 2013. 2. Hartz, P. A. Personal Communication. Baltimore, Md. 08/19/2016. 3. Ullrich, S., Munch, A., Neumann, S., Kremmer, E., Tatzelt, J., Lichtenthaler, S. F. The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein. J. Biol. Chem. 285: 20664-20674, 2010.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TMEM59

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Autre désignation: TMEM59

Sujet:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Transmembrane protein 59 is a protein that in humans is encoded by the TMEM59 gene. This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 44 kDa

ID gène: 9528