SHROOM1 anticorps (AA 371-807)

N° du produit ABIN7601525

Cet anticorps anti-SHROOM1 est un anticorps Lapin Polyclonal détectant SHROOM1 dans WB et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour SHROOM1 anticorps (AA 371-807) (ABIN7601525)

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHROOM1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SHROOM1 anticorps

Épitope: AA 371-807

Fonction: Anti-SHROOM1 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SHROOM1 Antibody Picoband® (ABIN7601525). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SHROOM1 recombinant protein (Position: R371-D807).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hagens, O., Ballabio, A., Kalscheuer, V., Kraehenbuhl, J.-P., Schiaffino, M. V., Smith, P., Staub, O., Hildebrand, J., Wallingford, J. B. A new standard nomenclature for proteins related to Apx and Shroom. BMC Cell Biol. 7: 18, 2006. Note: Electronic Article. 2. Lee, C., Scherr, H. M., Wallingford, J. B. Shroom family proteins regulate gamma-tubulin distribution and microtubule architecture during epithelial cell shape change. Development 134: 1431-1441, 2007. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXII. The complete sequences of 50 new cDNA clones which code for large proteins. DNA Res. 8: 319-327, 2001.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SHROOM1

Antigène: SHROOM1 (Shroom Family Member 1 (SHROOM1))

Autre désignation: SHROOM1

Sujet:

Synonyms: Mediator of RNA polymerase II transcription subunit 9, Mediator complex subunit 9, MED9, MED25,

Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Background: SHROOM family members play diverse roles in the development of the nervous system and other tissues. SHROOM1 is a PDZ domain-containing actin-binding protein that is required for neural tube morphogenesis. It facilitates neurulation by regulating the morphology of neurepithelial cells via the apical positioning of an actomyosin network in the neurepithelium. SHROOM1 is also expressed in pulmonary arterial smooth muscle cells and its expression is significantly decreased in mouse and human models of pulmonary arterial hypertension, suggesting that there may be a link between SHROOM1 expression and pulmonary arterial hypertension.

Poids moléculaire: 91 kDa

ID gène: 134549

UniProt: Q2M3G4