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HGD anticorps (AA 374-445)

Cet anticorps anti-HGD est un anticorps Souris Monoclonal détectant HGD dans WB, IHC et FACS. Adapté pour Humain.
N° du produit ABIN7601528

Aperçu rapide pour HGD anticorps (AA 374-445) (ABIN7601528)

Antigène

Voir toutes HGD Anticorps
HGD (Homogentisate 1,2-Dioxygenase (HGD))

Reactivité

  • 35
  • 19
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 47
  • 5
Souris

Clonalité

  • 47
  • 5
Monoclonal

Conjugué

  • 24
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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Cet anticorp HGD est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone

2F11E1
  • Épitope

    • 15
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    AA 374-445

    Fonction

    Anti-HGD Antibody Picoband® (monoclonal, 2F11E1)

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-HGD Antibody Picoband® (monoclonal, 2F11E1) (ABIN7601528). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E. coli-derived human HGD recombinant protein (Position: D374-N445).

    Isotype

    IgG2b
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Fernandez-Canon, J. M., Granadino, B., Beltran-Valero de Bernabe, D., Renedo, M., Fernandez-Ruiz, E., Penalva, M. A., Rodriguez de Cordoba, S. The molecular basis of alkaptonuria. Nature Genet. 14: 19-24, 1996. 2. Vilboux, T., Kayser, M., Introne, W., Suwannarat, P., Bernardini, I., Fischer, R., O'Brien, K., Kleta, R., Huizing, M., Gahl, W. A. Mutation spectrum of homogentisic acid oxidase (HGD) in alkaptonuria. Hum. Mutat. 30: 1611-1619, 2009.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    HGD (Homogentisate 1,2-Dioxygenase (HGD))

    Autre désignation

    HGD

    Sujet

    Synonyms: Ras-related protein Rab-5A, RAB5A, RAB5

    Tissue Specificity: Widely expressed in fetal and adult tissues.

    Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

    Poids moléculaire

    50 kDa

    ID gène

    3081

    UniProt

    Q93099
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