DHX9 anticorps (AA 396-759)

N° du produit ABIN7601604

Cet anticorps Lapin Polyclonal détecte spécifiquement DHX9 dans WB, ELISA, IHC, IF, ICC et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour DHX9 anticorps (AA 396-759) (ABIN7601604)

Antigène: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHX9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-DHX9 anticorps

Épitope: AA 396-759

Fonction: Anti-RNA Helicase A/DHX9 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for RNA Helicase A/DHX9 detection. Tested with WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA in Human,Mouse,Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RNA Helicase A/DHX9 recombinant protein (Position: E396-E759).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Abdelhaleem, M. M., Hameed, S., Klassen, D., Greenberg, A. H. Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles. J. Immun. 156: 2026-2035, 1996. 2. Aktas, T., Avsar Ilik, I., Maticzka, D., Bhardwaj, V., Pessoa Rodrigues, C., Mittler, G., Manke, T., Backofen, R., Akhtar, A. DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature 544: 115-119, 2017. 3. Lee, C. G., Hurwitz, J. A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3-prime to 5-prime ion. J. Biol. Chem. 267: 4398-4407, 1992.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur DHX9

Antigène: DHX9 (ATP-Dependent RNA Helicase A (DHX9))

Autre désignation: DHX9

Sujet:

Synonyms: ATP-dependent RNA helicase A, DEAH box protein 9, DExH-box helicase 9, Leukophysin, LKP, Nuclear DNA helicase II, NDH II, RNA helicase A, DHX9, DDX9

Tissue Specificity: Macrophages, peripheral blood leukocytes, lung, spleen and liver.

Background: ATP-dependent RNA helicase A (RHA, also known as DHX9, LKP, and NDHI) is an enzyme that in humans is encoded by the DHX9 gene. It is mapped to 1q25.3. This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.

Poids moléculaire: 141 kDa

ID gène: 1660

UniProt: Q08211