FLNB anticorps (AA 397-701)

N° du produit ABIN7601606

Cet anticorps anti-FLNB Monoclonal Souris (Clone 11E2D2) (ABIN7601606) détecte spécifiquement FLNB dans WB, IHC, IF et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FLNB anticorps (AA 397-701) (ABIN7601606)

Antigène: FLNB (Filamin B, beta (FLNB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLNB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 11E2D2

Détail du produit anti-FLNB anticorps

Épitope: AA 397-701

Fonction: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Filamin B/FLNB Antibody (monoclonal, 11E2D2) (ABIN7601606). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Filamin B/FLNB recombinant protein (Position: Q397-D701).

Isotype: IgG1

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur FLNB

Antigène: FLNB (Filamin B, beta (FLNB))

Autre désignation: FLNB

Sujet:

Synonyms: CMT2L, CRYAC, DHMN 2, DHMN2, E2IG1, H11, HMN 2, HMN2, HMN2A, HSB8, HSPB 8, HspB8

Tissue Specificity: Predominantly expressed in skeletal muscle and heart.

Background: Filamin B, beta (FLNB), also known as Filamin B, beta (truncated actin binding protein 278 homolog), is a cytoplasmic protein which in humans is encoded by the FLNB gene. This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3, boomerang dysplasia, autosomal dominant Larsen syndrome, and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Poids moléculaire: 278 kDa

ID gène: 2317

UniProt: O75369

Pathways: Maintenance of Protein Location