Calpain 3 anticorps (AA 42-764)
Aperçu rapide pour Calpain 3 anticorps (AA 42-764) (ABIN7601700)
Antigène
Voir toutes Calpain 3 (CAPN3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 42-764
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Fonction
- Anti-Calpain 3/CAPN3 Antibody
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Attributs du produit
- Anti-Calpain 3/CAPN3 Antibody (ABIN7601700). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human Calpain 3/CAPN3 recombinant protein (Position: I42-D764). Human CAPN3 shares 93.5% and 94.2% amino acid (aa) sequence identity with mouse and rat CAPN3, respectively.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- Calpain 3 (CAPN3)
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Autre désignation
- Calpain 3/CAPN3
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Sujet
- Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.
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Poids moléculaire
- 99 kDa
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ID gène
- 825
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UniProt
- P20807
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Antigène
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