VPS41 anticorps (AA 44-843)

N° du produit ABIN7601748

Cet anticorps Lapin Polyclonal détecte spécifiquement VPS41 dans ELISA, WB et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour VPS41 anticorps (AA 44-843) (ABIN7601748)

Antigène: VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VPS41 est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-VPS41 anticorps

Épitope: AA 44-843

Fonction: Anti-VPS41 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-VPS41 Antibody Picoband® (ABIN7601748). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human VPS41 recombinant protein (Position: Q44-R843).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/mL/1x10^6 cells, Human
ELISA, 0.1-0.5 μg/mL/mL, Human
1. Asensio, C. S., Sirkis, D. W., Maas, J. W., Jr., Egami, K., To, T.-L., Brodsky, F. M., Shu, X., Cheng, Y., Edwards, R. H. Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Dev. Cell 27: 425-437, 2013. 2. Cabrera, M., Langemeyer, L., Mari, M., Rethmeier, R., Orban, I., Perz, A., Brocker, C., Griffith, J., Klose, D., Steinhoff, H.-J., Reggiori, F., Engelbrecht-Vandre, S., Ungermann, C. Phosphorylation of a membrane curvature-sensing motif switches function of the HOPS subunit Vps41 in membrane tethering. J. Cell Biol. 191: 845-859, 2010. [PubMed: 21079247, images, related citations] [Full Text] 3. Hartz, P. A. Personal Communication. Baltimore, Md. 10/2/2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur VPS41

Antigène: VPS41 (Vacuolar Protein Sorting 41 Homolog (VPS41))

Autre désignation: VPS41

Sujet:

Synonyms: E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, E3 SUMO-protein transferase PIAS2, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor of activated STAT2, PIAS2, PIASX

Tissue Specificity: Mainly expressed in testis. Isoform 3 is expressed predominantly in adult testis, weakly in pancreas, embryonic testis and sperm, and at very low levels in other organs.

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known.

Poids moléculaire: 99 kDa

ID gène: 27072

UniProt: P49754