NCR1 anticorps (AA 55-258)

N° du produit ABIN7602013

L’anticorps Lapin Polyclonal anti-NCR1 a été validé pour ELISA et IHC. Il convient pour détecter NCR1 dans des échantillons de Humain et Souris.

Aperçu rapide pour NCR1 anticorps (AA 55-258) (ABIN7602013)

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCR1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NCR1 anticorps

Épitope: AA 55-258

Fonction: Anti-NCR1 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-NCR1 Antibody Picoband® (ABIN7602013). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NCR1 recombinant protein (Position: A55-R258).

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Gazit, R., Gruda, R., Elboim, M., Arnon, T. I., Katz, G., Achdout, H., Hanna, J., Qimron, U., Landau, G., Greenbaum, E., Zakay-Rones, Z., Porgador, A., Mandelboim, O. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1. Nature Immun. 7: 517-523, 2006. 2. Narni-Mancinelli, E., Jaeger, B. N., Bernat, C., Fenis, A., Kung, S., De Gassart, A., Mahmood, S., Gut, M., Heath, S. C., Estelle, J., Bertosio, E., Vely, F., Gastinel, L. N., Beutler, B., Malissen, B., Malissen, M., Gut, I. G., Vivier, E., Ugolini, S. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science 335: 344-348, 2012. 3. Pessino, A., Sivori, S., Bottino, C., Malaspina, A., Morelli, L., Moretta, L., Biassoni, R., Moretta, A. Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity. J. Exp. Med. 188: 953-960, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NCR1

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: NCR1

Sujet:

Synonyms: Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD335, NCR1, LY94

Tissue Specificity: Selectively expressed by both resting and activated NK cells.

Background: Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene. Predicted to be involved in cellular defense response, regulation of natural killer cell mediated cytotoxicity, and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome, anogenital venereal wart, hepatitis C, and lymphoproliferative syndrome.

Poids moléculaire: 36 kDa

ID gène: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity