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TXN2 anticorps (AA 60-166)

Cet anticorps anti-TXN2 est un anticorps Souris Monoclonal détectant TXN2 dans WB, IHC, IF, ICC et FACS. Adapté pour Humain, Rat et Souris.
N° du produit ABIN7602149

Aperçu rapide pour TXN2 anticorps (AA 60-166) (ABIN7602149)

Antigène

Voir toutes TXN2 Anticorps
TXN2 (Thioredoxin 2 (TXN2))

Reactivité

  • 34
  • 25
  • 10
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 50
  • 2
Souris

Clonalité

  • 47
  • 5
Monoclonal

Conjugué

  • 26
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp TXN2 est non-conjugé

Application

  • 45
  • 17
  • 16
  • 13
  • 13
  • 11
  • 11
  • 7
  • 5
  • 4
  • 3
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone

7B5
  • Épitope

    • 15
    • 12
    • 8
    • 6
    • 3
    • 1
    AA 60-166

    Fonction

    Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 7B5)

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Thioredoxin 2/TXN2 Antibody Picoband® (monoclonal, 7B5) (ABIN7602149). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human Thioredoxin 2/TXN2 recombinant protein (Position: T60-G166).

    Isotype

    IgG2b
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Benhar, M., Forrester, M. T., Hess, D. T., Stamler, J. S. Regulated protein denitrosylation by cytosolic and mitochondrial thioredoxins. Science 320: 1050-1054, 2008. 2. Chen, Y., Cai, J., Murphy, T. J., Jones, D. P. Overexpressed human mitochondrial thioredoxin confers resistance to oxidant-induced apoptosis in human osteosarcoma cells. J. Biol. Chem. 277: 33242-33248, 2002.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    TXN2 (Thioredoxin 2 (TXN2))

    Autre désignation

    TXN2

    Sujet

    Synonyms: Thioredoxin, mitochondrial, MTRX, Mt-Trx, Thioredoxin-2, TXN2, TRX2

    Tissue Specificity: Widely expressed in adult (at protein level) and fetal tissues.

    Background: Thioredoxin, mitochondrial also known as thioredoxin-2 is a protein that in humans is encoded by the TXN2 gene on chromosome 22. It is mapped to 22q12.3. This nuclear gene encodes a mitochondrial member of the thioredoxin family, a group of small multifunctional redox-active proteins. The encoded protein may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis.

    Poids moléculaire

    14 kDa

    ID gène

    25828

    UniProt

    Q99757

    Pathways

    Cell RedoxHomeostasis
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