PHACTR1 anticorps (AA 66-395)

N° du produit ABIN7602246

Cet anticorps Lapin Polyclonal détecte spécifiquement PHACTR1 dans WB, ELISA et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour PHACTR1 anticorps (AA 66-395) (ABIN7602246)

Antigène: PHACTR1 (Phosphatase and Actin Regulator 1 (PHACTR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHACTR1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PHACTR1 anticorps

Épitope: AA 66-395

Fonction: Anti-PHACTR1 Antibody Picoband®

Attributs du produit: Anti-PHACTR1 Antibody Picoband® (ABIN7602246). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PHACTR1 recombinant protein (Position: K66-E395). Human PHACTR1 shares 94.8% and 95.2% amino acid (aa) sequence identity with mouse and rat PHACTR1, respectively.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Allen, P. B., Greenfield, A. T., Svenningsson, P., Haspeslagh, D. C., Greengard, P. Phactrs 1-4: a family of protein phosphatase 1 and actin regulatory proteins. Proc. Nat. Acad. Sci. 101: 7187-7192, 2004. 2. de Ligt, J., Willemsen, M. H., van Bon, B. W. M., Kleefstra, T., Yntema, H. G., Kroes, T., Vulto-van Silfhout, A. T., Koolen, D. A., de Vries, P., Gilissen, C., del Rosario, M., Hoischen, A., Scheffer, H., de Vries, B. B. A., Brunner, H. G., Veltman, J. A., Vissers, L. E. L. M. Diagnostic exome sequencing in persons with severe intellectual disability. New Eng. J. Med. 367: 1921-1929, 2012. 3. Hamada, N., Ogaya, S., Nakashima, M., Nishijo, T., Sugawara, Y., Iwamoto, I., Ito, H., Maki, Y., Shirai, K., Baba, S., Maruyama, K., Saitsu, H., Kato, M., Matsumoto, N., Momiyama, T., Nagata, K. De novo PHACTR1 mutations in West syndrome and their pathophysiological effects. Brain 141: 3098-3114, 2018.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PHACTR1

Antigène: PHACTR1 (Phosphatase and Actin Regulator 1 (PHACTR1))

Autre désignation: PHACTR1

Sujet: Phosphatase and actin regulator 1 (PHACTR1) is a protein that in humans is encoded by the PHACTR1 gene on chromosome 6. The protein encoded by this gene is a member of the phosphatase and actin regulator family of proteins. This family member can bind actin and regulate the reorganization of the actin cytoskeleton. It plays a role in tubule formation and in endothelial cell survival. Polymorphisms in this gene are associated with susceptibility to myocardial infarction, coronary artery disease and cervical artery dissection. Alternative splicing of this gene results in multiple transcript variants.

Poids moléculaire: 69 kDa

ID gène: 221692

UniProt: Q9C0D0