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NFE2L3 anticorps (AA 66-653)

Cet anticorps anti-NFE2L3 est un anticorps Lapin Polyclonal détectant NFE2L3 dans WB et ELISA. Adapté pour Souris.
N° du produit ABIN7602254

Aperçu rapide pour NFE2L3 anticorps (AA 66-653) (ABIN7602254)

Antigène

Voir toutes NFE2L3 Anticorps
NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

Reactivité

  • 26
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Souris

Hôte

  • 26
Lapin

Clonalité

  • 26
Polyclonal

Conjugué

  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp NFE2L3 est non-conjugé

Application

  • 16
  • 13
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Épitope

    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 66-653

    Fonction

    Anti-Nfe2l3 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Nfe2l3 Antibody Picoband® (ABIN7602254). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived mouse Nfe2l3 recombinant protein (Position: E66-K653).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Mouse
    ELISA, 0.1-0.5 μg/mL, -
    1. Chevillard, G., Paquet, M., Blank, V. Nfe213 (Nrf3) deficiency predisposes mice to T-cell lymphoblastic lymphoma. Blood 117: 2005-2008, 2011. 2. Kobayashi, A., Ito, E., Toki, T., Kogame, K., Takahashi, S., Igarashi, K., Hayashi, N., Yamamoto, M. Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3. J. Biol. Chem. 274: 6443-6452, 1999.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    NFE2L3 (Nuclear Factor (erythroid-Derived 2)-Like 3 (NFE2L3))

    Autre désignation

    Nfe2l3

    Sujet

    Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

    Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

    Background: Nuclear factor (erythroid 2)-like factor 3, also known as NFE2L3 or 'NRF3', is a transcription factor that in humans is encoded by the Nfe2l3 gene. This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

    Poids moléculaire

    76 kDa

    ID gène

    18025
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