PRELP anticorps (AA 69-353)

N° du produit ABIN7602298

L’anticorps Lapin Polyclonal anti-PRELP a été validé pour WB, ELISA et FACS. Il convient pour détecter PRELP dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PRELP anticorps (AA 69-353) (ABIN7602298)

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRELP est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Détail du produit anti-PRELP anticorps

Épitope: AA 69-353

Fonction: Anti-PRELP Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PRELP Antibody Picoband® (ABIN7602298). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRELP recombinant protein (Position: I69-R353).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bengtsson, E., Neame, P. J., Heinegard, D., Sommarin, Y. The primary structure of a basic leucine-rich repeat protein, PRELP, found in connective tissues. J. Biol. Chem. 270: 25639-25644, 1995. 2. Grover, J., Chen, X.-N., Korenberg, J. R., Recklies, A. D., Roughley, P. J. The gene organization, chromosome location, and expression of a 55- kDa matrix protein (PRELP) of human articular cartilage. Genomics 38: 109-117, 1996.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur PRELP

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Autre désignation: PRELP

Sujet:

Synonyms: Cadherin-4, Retinal cadherin, R-CAD, R-cadherin, CDH4

Tissue Specificity: Expressed mainly in brain but also found in other tissues.

Background: Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Poids moléculaire: 65 kDa

ID gène: 5549

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process