NAPRT1 anticorps (AA 69-480)

N° du produit ABIN7602305

Cet anticorps anti-NAPRT1 est un anticorps Lapin Polyclonal détectant NAPRT1 dans WB et ELISA. Adapté pour Humain.

Aperçu rapide pour NAPRT1 anticorps (AA 69-480) (ABIN7602305)

Antigène: NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NAPRT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-NAPRT1 anticorps

Épitope: AA 69-480

Fonction: Anti-NAPRT Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-NAPRT Antibody Picoband® (ABIN7602305). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NAPRT recombinant protein (Position: A69-Q480).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Chowdhry, S., Zanca, C., Rajkumar, U., Koga, T., Diao, Y., Raviram, R., Liu, F., Turner, K., Yang, H., Brunk, E., Bi, J., Furnari, F., Bafna, V., Ren, B., Mischel, P. S. NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling. Nature 569: 570-575, 2019. 2. Hara, N., Yamada, K., Shibata, T., Osago, H., Hashimoto, T., Tsuchiya, M. Elevation of cellular NAD levels by nicotinic acid and involvement of nicotinic acid phosphoribosyltransferase in human cells. J. Biol. Chem. 282: 24574-24582, 2007.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur NAPRT1

Antigène: NAPRT1 (NAPRT) (Nicotinate phosphoribosyltransferase (NAPRT))

Autre désignation: NAPRT

Sujet:

Synonyms: Neutrophil defensin 1,Defensin, alpha 1,HNP-1,HP-1,HP1,HP 1-56,Neutrophil defensin 2,HNP-2,HP-2,HP2,DEFA1,DEF1, DEFA2, MRS,DEFA1B,

Tissue Specificity: Expressed in immature but not mature T-cells. Also found in CD34+ cells from peripheral blood, CD34+ precursors from umbilical cord blood and adult bone marrow.

Background: Nicotinic acid (NA, niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT, EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress.

Poids moléculaire: 58 kDa

ID gène: 93100