HDAC9 anticorps (AA 7-469)

N° du produit ABIN7602333

Cet anticorps Lapin Polyclonal détecte spécifiquement HDAC9 dans WB, ELISA, IF, ICC et FACS. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour HDAC9 anticorps (AA 7-469) (ABIN7602333)

Antigène: HDAC9 (Histone Deacetylase 9 (HDAC9))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC9 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-HDAC9 anticorps

Épitope: AA 7-469

Fonction: Anti-HDAC9 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-HDAC9 Antibody Picoband® (ABIN7602333). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HDAC9 recombinant protein (Position: S7-Q469).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mejat, A., Ramond, F., Bassel-Duby, R., Khochbin, S., Olson, E. N., Schaeffer, L. Histone deacetylase 9 couples neuronal activity to muscle chromatin acetylation and gene expression. Nature Neurosci. 8: 313-321, 2005. 2. Sparrow, D. B., Miska, E. A., Langley, E., Reynaud-Deonauth, S., Kotecha, S., Towers, N., Spohr, G., Kouzarides, T., Mohun, T. J. MEF-2 function is modified by a novel co-repressor, MITR. EMBO J. 18: 5085-5098, 1999. 3. Zhou, X., Marks, P. A., Rifkind, R. A., Richon, V. M. Cloning and characterization of a histone deacetylase, HDAC9. Proc. Nat. Acad. Sci. 98: 10572-10577, 2001.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur HDAC9

Antigène: HDAC9 (Histone Deacetylase 9 (HDAC9))

Autre désignation: HDAC9

Sujet:

Synonyms: Probetacellulin, Betacellulin, BTC, BTC

Tissue Specificity: Highly expressed in testis.

Background: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

Poids moléculaire: 150 kDa

ID gène: 9734

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development