KERA anticorps (AA 73-115)

N° du produit ABIN7602381

Cet anticorps Lapin Polyclonal détecte spécifiquement KERA dans WB et ELISA. Il présente une réactivité envers Souris et Rat.

Aperçu rapide pour KERA anticorps (AA 73-115) (ABIN7602381)

Antigène: KERA (Keratocan (KERA))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KERA est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-KERA anticorps

Épitope: AA 73-115

Fonction: Anti-Keratocan/KTN/Kera Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Keratocan/KTN/Kera Antibody Picoband® (ABIN7602381). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse Keratocan/KTN/Kera recombinant protein (Position: R73-K115).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Dudakova, L., Palos, M., Hardcastle, A. J., Liskova, P. Corneal endothelial findings in a Czech patient with compound heterozygous mutations in KERA. (Letter) Ophthalmic Genet. 35: 252-254, 2014. 2. Funderburgh, J. L., Perchellet, A. L., Swiergiel, J., Conrad, G. W., Justice, M. J. Keratocan (Kera), a corneal keratan sulfate proteoglycan, maps to the distal end of mouse chromosome 10. Genomics 52: 110-111, 1998. 3. Khan, A. O., Al-Saif, A., Kambouris, M. A novel KERA mutation associated with autosomal recessive cornea plana. Ophthal. Genet. 25: 147-152, 2004. Note: Erratum: Ophthal. Genet. 25: 289 only, 2004, Ophthal. Genet. 26: 195 only, 2005.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur KERA

Antigène: KERA (Keratocan (KERA))

Autre désignation: Kera

Sujet:

Synonyms: Protein Hook homolog 3, h-hook3, Hhk3, HOOK3

Tissue Specificity: Highly expressed in chromaffin cells of the adrenal medulla (at protein level). Detected in peripheral sympathetic ganglia (at protein level). Found in some paracrine cells in stomach and duodenum (at protein level).

Background: Keratocan (KTN) also known as keratan sulfate proteoglycan keratocan, is a protein that in humans is encoded by the KERA gene. The protein encoded by this gene is a keratan sulfate proteoglycan that is involved in corneal transparency. Defects in this gene are a cause of autosomal recessive cornea plana 2 (CNA2).

Poids moléculaire: 41 kDa

ID gène: 16545

UniProt: O35367

Pathways: Glycosaminoglycan Metabolic Process