MAEL anticorps (AA 73-347)
Aperçu rapide pour MAEL anticorps (AA 73-347) (ABIN7602386)
Antigène
Voir toutes MAEL AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 73-347
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Fonction
- Anti-MAEL Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-MAEL Antibody (ABIN7602386). Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human MAEL recombinant protein (Position: E73-Q347).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MAEL (Maelstrom Spermatogenic Transposon Silencer (MAEL))
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Autre désignation
- MAEL
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Sujet
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Synonyms: FERM domain-containing protein 6, Willin, FRMD6, C14orf31
Tissue Specificity: Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Background: The mammalian homolog of the Drosophila protein Maelstrom is expressed in the male germline and localizes to the sex body in spermatocytes and the chromatoid body in round spermatids. Similar to its expression in Drosophila, Maelstrom is a component of nuages, a germ-cell specific organelle and is thought to be essential for spermatogenesis and transposon repression during meiosis. In humans, Maelstrom has been found to be expressed only in the testis and in various cancer cell lines. Treatment of these cell lines with the demethylating agent 5'-Aza-2-Deoxycytidine significantly upregulated Maelstrom levels, indicating that its expression is regulated by DNA methylation.
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Poids moléculaire
- 49 kDa
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ID gène
- 84944
Antigène
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