MGAT2 anticorps (AA 81-427)

N° du produit ABIN7602526

L’anticorps Lapin Polyclonal anti-MGAT2 a été validé pour WB, IHC, ELISA et FACS. Il convient pour détecter MGAT2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MGAT2 anticorps (AA 81-427) (ABIN7602526)

Antigène: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGAT2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Détail du produit anti-MGAT2 anticorps

Épitope: AA 81-427

Fonction: Anti-MGAT2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-MGAT2 Antibody Picoband® (ABIN7602526). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MGAT2 recombinant protein (Position: Q81-K427).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Alazami, A. M., Monies, D., Meyer, B. F., Alzahrani, F., Hashem, M., Salih, M. A., Alkuraya, F. S. Congenital disorder of glycosylation IIa: the trouble with diagnosing a dysmorphic inborn error of metabolism. (Letter) Am. J. Med. Genet. 158A: 245-246, 2012. 2. Alkuraya, F. S. Mental retardation, growth retardation, unusual nose, and open mouth: an autosomal recessive entity. Am. J. Med. Genet. 152A: 2160-2163, 2010. 3. Cormier-Daire, V., Amiel, J., Vuillaumier-Barrot, S., Tan, J., Durand, G., Munnich, A., Le Merrer, M., Seta, N. Congenital disorders of glycosylation IIa cause growth retardation, mental retardation, and facial dysmorphism. J. Med. Genet. 37: 875-877, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur MGAT2

Antigène: MGAT2 (Mannosyl (Alpha-1,6-)-Glycoprotein beta-1,2-N-Acetylglucosaminyltransferase (MGAT2))

Autre désignation: MGAT2

Sujet:

Synonyms: RasGAP-activating-like protein 1, RAS protein activator like 1

Tissue Specificity: Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea (PubMed:9751798). Expressed in melanocytes (PubMed:23999003).

Background: Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT2 gene. The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Poids moléculaire: 50 kDa

ID gène: 4247

UniProt: Q10469