TOM1 anticorps (AA 84-480)

N° du produit ABIN7602556

L’anticorps Lapin Polyclonal anti-TOM1 a été validé pour WB, ELISA, IHC, IP, IF, FACS et ICC. Il convient pour détecter TOM1 dans des échantillons de Humain.

Aperçu rapide pour TOM1 anticorps (AA 84-480) (ABIN7602556)

Antigène: TOM1 (Target of Myb 1 (TOM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TOM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-TOM1 anticorps

Épitope: AA 84-480

Fonction: Anti-TOM1 Antibody Picoband®

Attributs du produit: Anti-TOM1 Antibody Picoband® (ABIN7602556). Tested in WB, IHC, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human TOM1 recombinant protein (Position: R84-K480). Human TOM1 shares 87.4% amino acid (aa) sequence identity with mouse TOM1.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunoprecipitation, 0.5-2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Burk, O., Worpenberg, S., Haenig, B., Klempnauer, K. H. tom-1, a novel v-Myb target gene expressed in AMV- and E26-transformed myelomonocytic cells. EMBO J. 16: 1371-1380, 1997. 2. Katoh, Y., Imakagura, H., Futatsumori, M., Nakayama, K. Recruitment of clathrin onto endosomes by the Tom1-Tollip complex. Biochem. Biophys. Res. Commun. 341: 143-149, 2006. 3. Keskitalo, S., Haapaniemi, E. M., Glumoff, V., Liu, X., Lehtinen, V., Fogarty, C., Rajala, H., Chiang, S. C., Mustjoki, S., Kovanen, P., Lohi, J., Bryceson, Y. T., Seppanen, M., Kere, J., Heiskanen, K., Varjosalo, M. Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease. NPJ Genomic Med. 4: 14, 2019.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur TOM1

Antigène: TOM1 (Target of Myb 1 (TOM1))

Autre désignation: TOM1

Sujet: Target of Myb protein 1 is a protein that in humans is encoded by the TOM1 gene. This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 54 kDa

ID gène: 10043

UniProt: O60784