PYHIN1 anticorps (AA 86-488)

N° du produit ABIN7602574

L’anticorps anti-PYHIN1 Polyclonal Lapin est utilisé pour la détection de PYHIN1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA, FACS, IHC, ICC et IF.

Aperçu rapide pour PYHIN1 anticorps (AA 86-488) (ABIN7602574)

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PYHIN1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-PYHIN1 anticorps

Épitope: AA 86-488

Fonction: Anti-PYHIN1 Antibody

Homologie: Human PYHIN1 shares 45.6% amino acid (aa) sequence identity with mouse PYHIN1.

Attributs du produit: Anti-PYHIN1 Antibody. Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PYHIN1 recombinant protein (Position: K86-H488). Human PYHIN1 shares 45.6% amino acid (aa) sequence identity with mouse PYHIN1.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, HHuman, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PYHIN1

Antigène: PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))

Autre désignation: PYHIN1

Sujet:

Background: The protein encoded by this gene belongs to the HIN-200 family of interferon-inducible proteins that share a 200-amino acid signature motif at their C-termini. HIN200 proteins are primarily nuclear and are involved in transcriptional regulation of genes important for cell cycle control, differentiation, and apoptosis. Downregulation of this gene is associated with breast cancer. This protein acts as a tumor suppressor by promoting ubiquitination and subsequent degradation of MDM2, which leads to stabilization of p53/TP53. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene Full Name: pyrin and HIN domain family member 1

Poids moléculaire: 55 kDa

ID gène: 149628

UniProt: Q6K0P9