GSG2 anticorps (AA 86-798)

N° du produit ABIN7602576

Cet anticorps Lapin Polyclonal détecte spécifiquement GSG2 dans WB, ELISA, ICC, IF et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GSG2 anticorps (AA 86-798) (ABIN7602576)

Antigène: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSG2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Détail du produit anti-GSG2 anticorps

Épitope: AA 86-798

Fonction: Anti-GSG2/HASPIN Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-GSG2/HASPIN Antibody Picoband® (ABIN7602576). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GSG2/HASPIN recombinant protein (Position: R86-K798). Human GSG2/HASPIN shares 65% amino acid (aa) sequence identity with mouse GSG2/HASPIN.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Dai, J., Sultan, S., Taylor, S. S., Higgins, J. M. G. The kinase haspin is required for mitotic histone H3 Thr 3 phosphorylation and normal metaphase chromosome alignment. Genes Dev. 19: 472-488, 2005. 2. Higgins, J. M. G. The haspin gene: location in an intron of the integrin alpha-E gene, associated transcription of an integrin alpha-E-derived RNA and expression in diploid as well as haploid cells. Gene 267: 55-69, 2001. 3. Kelly, A. E., Ghenoiu, C., Xue, J. Z., Zierhut, C., Kimura, H., Funabiki, H. Survivin reads phosphorylated histone H3 threonine 3 to activate the mitotic kinase Aurora B. Science 330: 235-239, 2010.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur GSG2

Antigène: GSG2 (Germ Cell Associated 2 (Haspin) (GSG2))

Autre désignation: HASPIN

Sujet:

Synonyms: HASPIN, GSG2, Serine/threonine-protein kinase haspin, EC 2.7.11.1, Germ cell-specific gene 2 protein, H-haspin, Haploid germ cell-specific nuclear protein kinase

Background: Enables ATP binding activity and histone H3T3 kinase activity. Involved in several processes, including mitotic sister chromatid cohesion, mitotic spindle assembly checkpoint signaling, and protein localization to chromosome, centromeric region. Located in centrosome, nucleoplasm, and spindle.

Poids moléculaire: 88 kDa

ID gène: 83903