HOXD10 anticorps (AA 9-252)

N° du produit ABIN7602619

L’anticorps Lapin Polyclonal anti-HOXD10 a été validé pour WB, ELISA et IHC. Il convient pour détecter HOXD10 dans des échantillons de Humain et Souris.

Aperçu rapide pour HOXD10 anticorps (AA 9-252) (ABIN7602619)

Antigène: HOXD10 (Homeobox D10 (HOXD10))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOXD10 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-HOXD10 anticorps

Épitope: AA 9-252

Fonction: Anti-HOXD10 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-HOXD10 Antibody Picoband® (ABIN7602619). Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HOXD10 recombinant protein (Position: A9-K252).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Dobbs, M. B., Gurnett, C. A., Pierce, B., Exner, G. U., Robarge, J., Morcuende, J. A., Cole, W. G., Templeton, P. A., Foster, B., Bowcock, A. M. HOXD10 M319K mutation in a family with isolated congenital vertical talus. J. Orthop. Res. 24: 448-453, 2006. 2. Johnson, R. L., Tabin, C. J. Molecular models for vertebrate limb development. Cell 90: 979-990, 1997. 3. Reddy, S. D. N., Ohshiro, K., Rayala, S. K., Kumar, R. MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its function. Cancer Res. 68: 8195-8200, 2008.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur HOXD10

Antigène: HOXD10 (Homeobox D10 (HOXD10))

Autre désignation: HOXD10

Sujet:

Synonyms: Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, RIPE3b1 factor, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA

Tissue Specificity: Preferentially expressed in regulatory T-cells (Tregs).

Background: Homeobox D10, also known as HOXD10, is a protein which in humans is encoded by the HOXD10 gene. This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Poids moléculaire: 40 kDa

ID gène: 3236

UniProt: P28358