ETF1 anticorps (AA 9-342)

N° du produit ABIN7602626

Cet anticorps anti-ETF1 est un anticorps Souris Monoclonal détectant ETF1 dans WB, IHC, IF, ICC et FACS. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour ETF1 anticorps (AA 9-342) (ABIN7602626)

Antigène: ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ETF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 3 E5

Détail du produit anti-ETF1 anticorps

Épitope: AA 9-342

Fonction: Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3E5)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-eRF1/ETF1 Antibody Picoband® (monoclonal, 3E5) (ABIN7602626). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human eRF1/ETF1 recombinant protein (Position: D9-K342).

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human, Mouse, Rat
1. Frolova, L., Le Goff, X., Rasmussen, H. H., Cheperegin, S., Drugeon, G., Kress, M., Arman, I., Haenni, A.-L., Celis, J. E., Philippe, M., Justesen, J., Kisselev, L. A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor. Nature 372: 701-703, 1994. 2. Guenet, L., Henry, C., Toutain, B., Dubourg, C., Le Gall, J. Y., David, V., Le Treut, A. Eukaryotic translation termination factor gene (ETF1/eRF1) maps at D5S500 in a commonly deleted region of chromosome 5q31 in malignant myeloid diseases. Cytogenet. Cell Genet. 88: 82-86, 2000. 3. Hansen, L. L., Jakobsen, C. G., Justesen, J. Assignment of the human translation termination factor 1 (ETF1) to 5q31.1 and of the proximal marker D5S1995 by radiation hybrid mapping. Cytogenet. Cell Genet. 87: 256-257, 1999.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur ETF1

Antigène: ETF1 (Eukaryotic Translation Termination Factor 1 (ETF1))

Autre désignation: ETF1

Sujet:

Synonyms: AW546468 antibody, C80305 antibody, MGC18200 antibody, MGC4569 antibody, MGC54054 antibody, OTTHUMP00000147628 antibody, OTTHUMP00000229864 antibody, OTTHUMP00000229865 antibody, OTTHUMP00000229866 antibody, OTTHUMP00000229870 antibody, OTTHUMP00000229871 antibody, OTTHUMP00000229872 antibody, Placental ribonuclease inhibitor antibody, Placental RNase inhibitor antibody, PRI antibody, RAI antibody, RI antibody, Ribonuclease inhibitor antibody, Ribonuclease/angiogenin inhibitor 1 antibody, Ribonuclease/angiogenin inhibitor antibody, RINI_HUMAN antibody, RNase inhibitor antibody, RNH 1 antibody, RNH antibody, RNH1 antibody, Rnh1 ribonuclease/angiogenin inhibitor 1 antibody

Background: Eukaryotic translation termination factor 1 (eRF1), also known asTB3-1, is a protein that in humans is encoded by the ETF1 gene. It is mapped to 5q31.2. This gene encodes a class-1 polypeptide chain release factor. The encoded protein plays an essential role in ing termination of mRNA translation from the termination codons UAA, UAG and UGA. This protein is a component of the SURF complex which promotes degradation of prematurely terminated mRNAs via the mechanism of nonsense-mediated mRNA decay (NMD). Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 6, 7, and X.

Poids moléculaire: 49 kDa

ID gène: 2107

UniProt: P62495