LYPD3 anticorps (AA 90-392)
Aperçu rapide pour LYPD3 anticorps (AA 90-392) (ABIN7602645)
Antigène
Voir toutes LYPD3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 90-392
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Fonction
- Anti-LYPD3 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human ILKAP shares 98%,98.7% amino acid (aa) sequence identity with mouse,rat ILKAP,respectively.
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Attributs du produit
- Anti-LYPD3 Antibody. Tested in ELISA, IF, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human ILKAP recombinant protein (Position: E90-H392). Human ILKAP shares 98% and 98.7% amino acid (aa) sequence identity with mouse and rat ILKAP, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human, Rat Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- LYPD3 (LY6/PLAUR Domain Containing 3 (LYPD3))
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Autre désignation
- LYPD3
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Sujet
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Background: Ly6/PLAUR domain-containing protein 3 is a protein that in humans is encoded by the LYPD3 gene. Ly6 / PLAUR domain-containing protein 3, also known as GPI-anchored metastasis-associated protein C4.4A homolog, Matrigel-induced gene C4 protein, MIG-C4, and LYPD3, is a cell membrane protein that contains two UPAR/Ly6 domains. Human LYPD3 contains two UPAR/Ly6 domains. LYPD3 is expressed in the placenta, skin, and urothelium. It is found in suprabasal keratinocytes of chronic wounds. Weak expression of LYPD3 is found in the esophagus and peripheral blood mononuclear cells. It is found in the majority of primary and metastatic transitional cell carcinomas (TCCs) and as well in breast cancer tissues, but not in adjacent normal tissues. High expression of LYPD3 is found in the tumor component of some noninvasive superficial lesions and invasive and metastatic urothelial cancers. LYPD3 is up-regulated in migrating keratinocytes during epithelisation of incisional skin wounds. LYPD3 supports cell migration. It may be involved in urothelial cell-matrix interactions. It may also be involved in tumor progression.
Gene Full Name: LY6/PLAUR domain containing 3
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Poids moléculaire
- 75 kDa
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ID gène
- 27076
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UniProt
- O95274
Antigène
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