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E2F3 anticorps (AA 91-465)

Cet anticorps Lapin Polyclonal détecte spécifiquement E2F3 dans WB, ELISA, IHC et FACS. Il présente une réactivité envers Humain, Souris et Rat.
N° du produit ABIN7602654

Aperçu rapide pour E2F3 anticorps (AA 91-465) (ABIN7602654)

Antigène

Voir toutes E2F3 Anticorps
E2F3

Reactivité

  • 74
  • 65
  • 37
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Souris, Rat

Hôte

  • 88
  • 4
  • 1
Lapin

Clonalité

  • 90
  • 3
Polyclonal

Conjugué

  • 28
  • 7
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Cet anticorp E2F3 est non-conjugé

Application

  • 75
  • 39
  • 39
  • 35
  • 10
  • 9
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • Épitope

    • 15
    • 15
    • 15
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 91-465

    Fonction

    Anti-E2F3 Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-E2F3 Antibody Picoband® (ABIN7602654). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human E2F3 recombinant protein (Position: A91-S465).

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Chen, D., Pacal, M., Wenzel, P., Knoepfler, P. S., Leone, G., Bremner, R. Division and apoptosis of E2f-deficient retinal progenitors. Nature 462: 925-929, 2009. 2. Chong, J.-L., Wenzel, P. L., Saenz-Robles, M. T., Nair, V., Ferrey, A., Hagan, J. P., Gomez, Y. M., Sharma, N., Chen, H.-Z., Ouseph, M., Wang, S.-H., Trikha, P., and 10 others. E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells. Nature 462: 930-934, 2009.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    E2F3

    Sujet

    Synonyms: Transcription factor E2F3,E2F-3,E2F3,KIAA0075,

    Tissue Specificity: Expressed in skeletal muscle, kidney, heart, placenta, liver, thymus, lung, and ovary, with little or no expression in other tissues.

    Background: Transcription factor E2F3, also known as KIAA0075, is a protein that in humans is encoded by the E2F3 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. By fluorescence in situ hybridization, E2F3 gene is mapped to 6q22.3. The induction of specific E2F activities is an essential component in the MYC pathways that control cell proliferation and cell fate decisions. This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts ly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle.

    Poids moléculaire

    45 kDa

    ID gène

    1871

    UniProt

    O00716
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