IL18RAP anticorps (C-Term)

N° du produit ABIN7602806

Cet anticorps anti-IL18RAP est un anticorps Lapin Polyclonal détectant IL18RAP dans WB. Adapté pour Humain.

Aperçu rapide pour IL18RAP anticorps (C-Term) (ABIN7602806)

Antigène: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL18RAP est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL18RAP anticorps

Épitope: C-Term

Fonction: Anti-IL-18R Beta/IL-18RAP Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-IL-18R Beta/IL-18RAP Antibody Picoband® (ABIN7602806). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human IL-18R Beta/IL-18RAP, which shares 84.4% amino acid (aa) sequence identity with both mouse and rat IL-18R Beta/IL-18RAP.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
1. Born, T. L., Thomassen, E., Bird, T. A., Sims, J. E. Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling. J. Biol. Chem. 273: 29445-29450, 1998. 2. Koskinen, L. L. E., Einarsdottir, E., Dukes, E., Heap, G. A. R., Dubois, P., Korponay-Szabo, I. R., Kaukinen, K., Kurppa, K., Ziberna, F., Vatta, S., Not, T., Ventura, A., and 9 others. Association study of the IL18RAP locus in three European populations with coeliac disease. Hum. Molec. Genet. 18: 1148-1155, 2009.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.005 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur IL18RAP

Antigène: IL18RAP (Interleukin 18 Receptor Accessory Protein (IL18RAP))

Autre désignation: IL18RAP

Sujet:

Synonyms: Sodium channel subunit beta-4, SCN4B

Tissue Specificity: Expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Expressed in the atrium.

Background: Interleukin 18 receptor accessory protein, also known as IL18RAP and CDw218b (cluster of differentiation w218b), is a human gene. The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Poids moléculaire: 72 kDa

ID gène: 8807

UniProt: O95256