GP6 anticorps (C-Term)

N° du produit ABIN7602888

Cet anticorps Lapin Polyclonal détecte spécifiquement GP6 dans WB et FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour GP6 anticorps (C-Term) (ABIN7602888)

Antigène: GP6 (Glycoprotein VI (Platelet) (GP6))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GP6 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-GP6 anticorps

Épitope: C-Term

Fonction: Anti-GP6 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-GP6 Antibody Picoband® (ABIN7602888). Tested in WB, Flow Cytometry applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse GP6. Mouse GP6 shares 75% amino acid (aa) sequence identity with human GP6.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
1. Boilard, E., Nigrovic, P. A., Larabee, K., Watts, G. F. M., Coblyn, J. S., Weinblatt, M. E., Massarotti, E. M., Remold-O'Donnell, E., Farndale, R. W., Ware, J., Lee, D. M. Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science 327: 580-583, 2010. 2. Dumont, B., Lasne, D., Rothschild, C., Bouabdelli, M., Ollivier, V., Oudin, C., Ajzenberg, N., Grandchamp, B., Jandrot-Perrus, M. Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations. Blood 114: 1900-1903, 2009. 3. zumi, Y., Uchiyama, T., Takayama, H. Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI. Biochem. Biophys. Res. Commun. 277: 27-36, 2000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur GP6

Antigène: GP6 (Glycoprotein VI (Platelet) (GP6))

Autre désignation: GP6

Sujet:

Synonyms: GP6, Platelet glycoprotein VI, GPVI, Glycoprotein 6

Background: Enables collagen binding activity and collagen receptor activity. Acts upstream of or within collagen-activated tyrosine kinase receptor signaling pathway, peptidyl-tyrosine phosphorylation, and platelet aggregation. Located in cell surface and plasma membrane. Is expressed in bone marrow, femur, liver, and spleen. Human ortholog(s) of this gene implicated in blood platelet disease (multiple), coronary artery disease (multiple), and type 2 diabetes mellitus. Orthologous to human GP6 (glycoprotein VI platelet).

Poids moléculaire: 35 kDa

ID gène: 243816

UniProt: P0C191