SAP30 anticorps (C-Term)

N° du produit ABIN7602922

L’anticorps Lapin Polyclonal anti-SAP30 a été validé pour WB et FACS. Il convient pour détecter SAP30 dans des échantillons de Humain.

Aperçu rapide pour SAP30 anticorps (C-Term) (ABIN7602922)

Antigène: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAP30 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SAP30 anticorps

Épitope: C-Term

Fonction: Anti-SAP30 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SAP30 Antibody Picoband® (ABIN7602922). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SAP30.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Gross, M. B. Personal Communication. Baltimore, Md. 7/25/2012. 2. Laherty, C. D., Billin, A. N., Lavinsky, R. M., Yochum, G. S., Bush, A. C., Sun, J.-M., Mullen, T.-M., Davie, J. R., Rose, D. W., Glass, C. K., Rosenfeld, M. G., Ayer, D. E., Eisenman, R. N. SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Molec. Cell. 2: 33-42, 1998. 3. Zhang, Y., Sun, Z.-W., Iratni, R., Erdjument-Bromage, H., Tempst, P., Hampsey, M., Reinberg, D. SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex. Molec. Cell 1: 1021-1031, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SAP30

Antigène: SAP30 (Sin3A-Associated Protein, 30kDa (SAP30))

Autre désignation: SAP30

Sujet:

Synonyms: Phospholipid-transporting ATPase IG (EC:7.6.2.1), ATPase IQ, ATPase class VI type 11C, P4-ATPase flippase complex alpha subunit ATP11C, ATP11C, ATPIG, ATPIQ

Tissue Specificity: Widely expressed.

Background: Sin3A-associated protein, 30 kDa, also known as SAP30, is a protein which in humans is encoded by the SAP30 gene. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP18, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This complex is active in deacetylating core histone octamers, but inactive in deacetylating nucleosomal histones. A pseudogene of this gene is located on chromosome 3.

Poids moléculaire: 28 kDa

ID gène: 8819

UniProt: O75446