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ALOX5AP anticorps (Middle Region)

Cet anticorps anti-ALOX5AP est un anticorps Lapin Polyclonal détectant ALOX5AP dans WB, FACS, IF et ICC. Adapté pour Humain.
N° du produit ABIN7603016

Aperçu rapide pour ALOX5AP anticorps (Middle Region) (ABIN7603016)

Antigène

Voir toutes ALOX5AP Anticorps
ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

Reactivité

  • 8
  • 2
  • 1
Humain

Hôte

  • 6
  • 3
Lapin

Clonalité

  • 8
  • 1
Polyclonal

Conjugué

  • 8
  • 1
Cet anticorp ALOX5AP est non-conjugé

Application

  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Épitope

    • 3
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Fonction

    Anti-ALOX5AP Antibody Picoband®

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-ALOX5AP Antibody Picoband® (ABIN7603016). Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence in the middle region of human ALOX5AP, identical to the related mouse and rat sequences.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.25-0.5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. Dixon, R. A. F., Diehl, R. E., Opas, E., Rands, E., Vickers, P. J., Evans, J. F., Gillard, J. W., Miller, D. K. Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis. Nature 343: 282-284, 1990. 2. Ferguson, A. D., McKeever, B. M., Xu, S., Wisniewski, D., Miller, D. K., Yamin, T.-T., Spencer, R. H., Chu, L., Ujjainwalla, F., Cunningham, B. R., Evans, J. F., Becker, J. W. Crystal structure of inhibitor-bound human 5-lipoxygenase-activating protein. Science 317: 510-512, 2007. 3. Kennedy, B. P., Diehl, R. E., Boie, Y., Adam, M., Dixon, R. A. F. Gene characterization and promoter analysis of the human 5-lipoxygenase-activating protein (FLAP). J. Biol. Chem. 266: 8511-8516, 1991.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Antigène

    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

    Autre désignation

    ALOX5AP

    Sujet

    Synonyms: ALOX5AP, FLAP, Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein

    Background: This gene encodes a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

    Poids moléculaire

    18 kDa

    ID gène

    241

    UniProt

    P20292
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