SH3GL3 anticorps (Middle Region)

N° du produit ABIN7603091

Cet anticorps anti-SH3GL3 est un anticorps Lapin Polyclonal détectant SH3GL3 dans WB et FACS. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour SH3GL3 anticorps (Middle Region) (ABIN7603091)

Antigène: SH3GL3 (Endophilin-A3 (SH3GL3))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3GL3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-SH3GL3 anticorps

Épitope: Middle Region

Fonction: Anti-SH3GL3 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SH3GL3 Antibody Picoband® (ABIN7603091). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human SH3GL3, which shares 95.8% amino acid (aa) sequence identity with mouse and rat SH3GL3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Giachino, C., Lantelme, E., Lanzetti, L., Saccone, S., Della Valle, G., Migone, N. A novel SH3-containing human gene family preferentially expressed in the central nervous system. Genomics 41: 427-434, 1997. 2. Li, S., Qiao, Y., Di, Q., Le, X., Zhang, L., Zhang, X., Zhang, C., Cheng, J., Zong, S., Koide, S. S., Miao, S., Wang, L. Interaction of SH3P13 and DYDC1 protein: a germ cell component that regulates acrosome biogenesis during spermiogenesis. Europ. J. Cell Biol. 88: 509-520, 2009. Note: Erratum: Europ. J. Cell Biol. 98: 51-52, 2019. 3. Petrelli, A., Gilestro, G. F., Lanzardo, S., Comoglio, P. M., Migone, N., Giordano, S. The endophilin-CIN85-Cbl complex mediates ligand-dependent downregulation of c-Met. Nature 416: 187-190, 2002.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur SH3GL3

Antigène: SH3GL3 (Endophilin-A3 (SH3GL3))

Autre désignation: SH3GL3

Sujet:

Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

Background: Endophilin-A3 is a protein that in humans is encoded by the SH3GL3 gene. Enables identical protein binding activity. Predicted to be involved in synaptic vesicle uncoating. Predicted to be located in acrosomal vesicle, early endosome membrane, and presynapse. Predicted to be part of early endosome. Predicted to be active in glutamatergic synapse, postsynaptic density, intracellular component, and postsynaptic endosome.

Poids moléculaire: 42 kDa

ID gène: 6457

UniProt: Q99963