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RNH1 anticorps (N-Term)

L’anticorps Souris Monoclonal anti-RNH1 a été validé pour WB, IHC, IF, FACS et ICC. Il convient pour détecter RNH1 dans des échantillons de Humain.
N° du produit ABIN7603117

Aperçu rapide pour RNH1 anticorps (N-Term) (ABIN7603117)

Antigène

Voir toutes RNH1 Anticorps
RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reactivité

  • 57
  • 26
  • 25
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 48
  • 12
Souris

Clonalité

  • 51
  • 9
Monoclonal

Conjugué

  • 33
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp RNH1 est non-conjugé

Application

  • 54
  • 18
  • 17
  • 14
  • 13
  • 13
  • 11
  • 10
  • 7
  • 6
  • 3
  • 2
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone

4F3
  • Épitope

    • 16
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Fonction

    Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3)

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (monoclonal, 4F3) (ABIN7603117). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

    Isotype

    IgG2b
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 717-21. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 175-8.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

    Autre désignation

    RNH1

    Sujet

    Synonyms: AW546468 antibody, C80305 antibody, MGC18200 antibody, MGC4569 antibody, MGC54054 antibody, OTTHUMP00000147628 antibody, OTTHUMP00000229864 antibody, OTTHUMP00000229865 antibody, OTTHUMP00000229866 antibody, OTTHUMP00000229870 antibody, OTTHUMP00000229871 antibody, OTTHUMP00000229872 antibody, Placental ribonuclease inhibitor antibody, Placental RNase inhibitor antibody, PRI antibody, RAI antibody, RI antibody, Ribonuclease inhibitor antibody, Ribonuclease/angiogenin inhibitor 1 antibody, Ribonuclease/angiogenin inhibitor antibody, RINI_HUMAN antibody, RNase inhibitor antibody, RNH 1 antibody, RNH antibody, RNH1 antibody, Rnh1 ribonuclease/angiogenin inhibitor 1 antibody

    Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

    Poids moléculaire

    45 kDa

    ID gène

    6050

    UniProt

    P13489
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