FGG anticorps (N-Term)

N° du produit ABIN7603146

Cet anticorps Souris Monoclonal détecte spécifiquement FGG dans WB, ICC et IF. Il présente une réactivité envers Humain.

Aperçu rapide pour FGG anticorps (N-Term) (ABIN7603146)

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGG est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 5H9

Détail du produit anti-FGG anticorps

Épitope: N-Term

Fonction: Anti-FGG Antibody Picoband® (monoclonal, 5H9)

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FGG Antibody Picoband® (monoclonal, 5H9) (ABIN7603146). Tested in IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human FGG, different from the related mouse sequence by two amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG2b

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Budzynski, A. Z., Marder, V. J., Menache, D., Guillin, M.-C. Defect in the gamma polypeptide chain of a congenital abnormal fibrinogen (Paris I). Nature 252: 66-68, 1974. 2. Ebert, R. F., Bell, W. R. Fibrinogen Baltimore III: congenital dysfibrinogenemia with a shortened gamma-subunit. Thromb. Res. 51: 251-258, 1988. 3. Fornace, A. J., Jr., Cummings, D. E., Comeau, C. M., Kant, J. A., Crabtree, G. R. Structure of the human gamma-fibrinogen gene: alternate mRNA splicing near the 3-prime end of the gene produces gamma-A and gamma-B forms of gamma-fibrinogen. J. Biol. Chem. 259: 12826-12830, 1984.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur FGG

Antigène: FGG (Fibrinogen gamma Chain (FGG))

Autre désignation: FGG

Sujet:

Synonyms: Collagen alpha-1 (III) chain, COL3A1

Tissue Specificity: Expressed in T- and natural killer cells. Also present in early thymocytes and pro/pre B-cells.

Background: Fibrinogen gamma chain, also known as FGG, is a human gene found on Chromosome 4. The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in transcript variants encoding different isoforms.

Poids moléculaire: 52 kDa

ID gène: 2266

UniProt: P02679