GATA3 anticorps (N-Term)
Aperçu rapide pour GATA3 anticorps (N-Term) (ABIN7603171)
Antigène
Voir toutes GATA3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Fonction
- Anti-GATA3 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-GATA3 Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human GATA3, which shares 86.4% and 90.9% amino acid (aa) sequence identity with mouse and rat GATA3, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 4 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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Autre désignation
- GATA3
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Sujet
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Background: Trans-acting T-cell-specific transcription factor GATA-3, also named HDR or GATA3, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of IL-4, IL-5, and IL-13 from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
Gene Full Name: GATA binding protein 3
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Poids moléculaire
- 50 kDa
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ID gène
- 2625
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UniProt
- P23771
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Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Antigène
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