ACP2 anticorps (N-Term)

N° du produit ABIN7603192

L’anticorps Lapin Polyclonal anti-ACP2 a été validé pour WB. Il convient pour détecter ACP2 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ACP2 anticorps (N-Term) (ABIN7603192)

Antigène: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACP2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ACP2 anticorps

Épitope: N-Term

Fonction: Anti-ACP2 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-ACP2 Antibody Picoband® (ABIN7603192). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ACP2, which shares 100% and 96.4% amino acid (aa) sequence identity with mouse and rat ACP2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
1. Beckman, G., Beckman, L., Tarnvik, A. A rare subunit variant shared by five acid phosphatase isozymes from human leukocytes and placentae. Hum. Hered. 20: 81-85, 1970. 2. Bruns, G. A. P., Gerald, P. S. Human acid phosphatase in somatic cell hybrids. Science 184: 480-482, 1974. 3. Harris, H., Hopkinson, D. A., Robson, E. B. The incidence of rare alleles determining electrophoretic variants: data on 43 enzyme loci in man. Ann. Hum. Genet. 37: 237-253, 1974.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ACP2

Antigène: ACP2 (Acid Phosphatase 2, Lysosomal (ACP2))

Autre désignation: ACP2

Sujet:

Synonyms: AP-2 complex subunit beta,AP105B,Adaptor protein complex AP-2 subunit beta,Adaptor-related protein complex 2 subunit beta,Beta-2-adaptin,Beta-adaptin,Clathrin assembly protein complex 2 beta large chain,Plasma membrane adaptor HA2/AP2 adaptin beta subunit,AP2B1,ADTB2, CLAPB1,

Tissue Specificity: Widely expressed, at a low level, and the highest expression is observed in skeletal muscle and brain. Also detected in fetal liver.

Background: Lysosomal acid phosphatase is an enzyme that in humans is encoded by the ACP2 gene. The protein encoded by this gene belongs to the histidine acid phosphatase family, which hydrolyze orthophosphoric monoesters to alcohol and phosphate. This protein is localized to the lysosomal membrane, and is chemically and genetically distinct from the red cell acid phosphatase. Mice lacking this gene showed multiple defects, including bone structure alterations, lysosomal storage defects, and an increased tendency towards seizures. An enzymatically-inactive allele of this gene in mice showed severe growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype. Alternatively spliced transcript variants have been found for this gene. A C-terminally extended isoform is also predicted to be produced by the use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism.

Poids moléculaire: 76 kDa

ID gène: 53

UniProt: P11117