CGA anticorps (N-Term)

N° du produit ABIN7603204

L’anticorps Lapin Polyclonal anti-CGA a été validé pour WB, IHC et FACS. Il convient pour détecter CGA dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour CGA anticorps (N-Term) (ABIN7603204)

Antigène: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CGA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Détail du produit anti-CGA anticorps

Épitope: N-Term

Fonction: Anti-Chromogranin A/CGA Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Chromogranin A/CGA Antibody Picoband® (ABIN7603204). Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Chromogranin A/CGA, which shares 78.3% amino acid (aa) sequence identity with mouse Chromogranin A/CGA.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Boothby, M., Ruddon, R. W., Anderson, C., McWilliams, D., Boime, I. A single gonadotropin alpha-subunit gene in normal tissue and tumor-derived cell lines. J. Biol. Chem. 256: 5121-5127, 1981. 2. Bordelon, M., Kohler, P. O. Synthesis of human glycoprotein hormone in somatic cell hybrids. (Abstract) J. Cell Biol. 67: 37A only, 1975. 3. Bordelon-Riser, M. E., Siciliano, M. J., Kohler, P. O. Necessity for two human chromosomes for human chorionic gonadotropin production in human-mouse hybrids. Somat. Cell Genet. 5: 597-613, 1979.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur CGA

Antigène: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Autre désignation: CGA

Sujet:

Synonyms: CGA, Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, CG-alpha, Follicle-stimulating hormone alpha chain, FSH-alpha, Follitropin alpha chain, Luteinizing hormone alpha chain, LSH-alpha, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, TSH-alpha, Thyrotropin alpha chain

Background: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 17 kDa

ID gène: 1081

UniProt: P01215

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism