DMPK anticorps (N-Term)

N° du produit ABIN7603213

L’anticorps anti-DMPK Polyclonal produit chez le Lapin a été validé pour WB. Il convient pour la détection de DMPK dans des échantillons provenant de Souris et Rat. }

Aperçu rapide pour DMPK anticorps (N-Term) (ABIN7603213)

Antigène: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DMPK est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DMPK anticorps

Épitope: N-Term

Fonction: Anti-DMPK Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-DMPK Antibody (ABIN7603213). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human DMPK.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Mouse, Rat

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur DMPK

Antigène: DMPK (Dystrophia Myotonica-Protein Kinase (DMPK))

Autre désignation: DMPK

Sujet:

Synonyms: DMPK, DM1PK, MDPK, Myotonin-protein kinase, MT-PK, EC 2.7.11.1, DM-kinase, DMK, DM1 protein kinase, DMPK, Myotonic dystrophy protein kinase

Background: The protein encoded by this gene is a serine/threonine protein kinase that contains coiled-coil and C-terminal membrane association domains. In the embryonic mouse, it is found in cardiac and skeletal myocytes where it appears to play a role in myogenesis. In adults, the transcript is localized to several tissues including brain, heart, and skeletal and smooth muscle, and a function in cytoskeletal remodeling has been described. Transcripts with expanded CUG repeats in the 3' untranslated region mediate alternative splicing of several genes and sequester RNA binding proteins and RNA transcripts that contain CAG repeats, resulting in myotonic dystrophy, an autosomal dominant neuromuscular disorder. Alternative splicing results in multiple protein coding and non-coding transcript variants.

Poids moléculaire: 70 kDa

ID gène: 13400

UniProt: P54265

Pathways: Regulation of Muscle Cell Differentiation, Synaptic Membrane, Skeletal Muscle Fiber Development