Histone H3.3 anticorps (pTyr3)
Aperçu rapide pour Histone H3.3 anticorps (pTyr3) (ABIN7603448)
Antigène
Voir toutes Histone H3.3 (H3F3A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- pTyr3
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Fonction
- Anti-Phospho-Histone H3 (T3) H3F3A Monoclonal Antibody
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Attributs du produit
- Anti-Phospho-Histone H3 (T3) H3F3A Monoclonal Antibody (ABIN7603448). Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human Phospho-Histone H3 (T3) H3 Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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Isotype
- IgG
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Indications d'application
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WB 1:500-1:2000
IHC 1:50-1:200
ICC/IF 1:50-1:200
FC 1:50 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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Autre désignation
- H3F3A
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Sujet
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Synonyms: Red fluorescent protein eqFP611,GFP-like chromoprotein,
Tissue Specificity: Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (ESC). Levels rapidly diminish as soon as ESC's differentiate (at protein levels). Expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes. Found on the surface of adenocarcinoma. .
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Poids moléculaire
- 15 kDa
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UniProt
- P84243
Antigène
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