SIRT2 anticorps

N° du produit ABIN7606297

L’anticorps anti-SIRT2 Monoclonal Lapin est utilisé pour la détection de SIRT2 dans des échantillons de Humain et Rat. Il a été validé pour WB.

Aperçu rapide pour SIRT2 anticorps (ABIN7606297)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB)

Clone: HCA-19

Détail du produit anti-SIRT2 anticorps

Fonction: Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody

Attributs du produit: Anti-SIRT2/Sirtuin 2 Rabbit Monoclonal Antibody (ABIN7606297). Tested in WB application. This antibody reacts with Human, Rat.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human SIRT2

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SIRT2

Sujet:

Synonyms: NAD-dependent protein deacetylase sirtuin-2,3.5.1.-,Regulatory protein SIR2 homolog 2,SIR2-like protein 2,SIRT2,SIR2L, SIR2L2,

Tissue Specificity: Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network. .

Poids moléculaire: 160-180 kDa