PD-1 anticorps (Biotin)

N° du produit ABIN7608071

L’anticorps anti-PD-1 Monoclonal produit chez le Lapin a été validé pour ELISA. Il convient pour la détection de PD-1 dans des échantillons provenant de Chien. }

Aperçu rapide pour PD-1 anticorps (Biotin) (ABIN7608071)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Chien

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est conjugé à/à la Biotin

Application: ELISA

Clone: 4-00E-01

Détail du produit anti-PD-1 anticorps (Biotin)

Fonction: Biotinylated Anti-Canine PD-1 antibody(4E1), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Information d'application

Indications d'application: ELISA 1/5000-10000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: PD-1

Sujet: Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells, it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]

NCBI Accession: NP_001301026

Pathways: Cancer Immune Checkpoints