BRMS1L anticorps (AA 151-246) (Biotin)

N° du produit ABIN730935

Cet anticorps anti-BRMS1L est un anticorps Polyclonal produit chez le Lapin, détectant BRMS1L dans WB, ELISA, IHC (p) et IHC (fro). Convient pour Humain.

Aperçu rapide pour BRMS1L anticorps (AA 151-246) (Biotin) (ABIN730935)

Antigène: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRMS1L est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BRMS1L anticorps (Biotin)

Épitope: AA 151-246

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BRMS-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur BRMS1L

Antigène: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Autre désignation: BRMS-1

Sujet:

Synonyms: Breast cancer metastasis-suppressor 1, BRMS1

Background: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

ID gène: 25855

UniProt: Q9HCU9