BRMS1L anticorps (AA 151-246) (Cy5)

N° du produit ABIN730937

L’anticorps Lapin Polyclonal anti-BRMS1L a été validé pour WB, IF (cc) et IF (p). Il convient pour détecter BRMS1L dans des échantillons de Humain.

Aperçu rapide pour BRMS1L anticorps (AA 151-246) (Cy5) (ABIN730937)

Antigène: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BRMS1L est conjugé à/à la Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-BRMS1L anticorps (Cy5)

Épitope: AA 151-246

Réactivité croisée: Humain

Homologie: Mouse,Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BRMS-1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur BRMS1L

Antigène: BRMS1L (Breast Cancer Metastasis-Suppressor 1-Like (BRMS1L))

Autre désignation: BRMS-1

Sujet:

Synonyms: Breast cancer metastasis-suppressor 1, BRMS1

Background: Transcriptional repressor. Down-regulates transcription activation by NF-kappa-B by promoting the deacetylation of RELA at 'Lys-310'. Promotes HDAC1 binding to promoter regions. Down-regulates expression of anti-apoptotic genes that are controlled by NF-kappa-B. Promotes apoptosis in cells that have inadequate adherence to a substrate, a process called anoikis, and may thereby inhibit metastasis. May be a mediator of metastasis suppression in breast carcinoma.

ID gène: 25855

UniProt: Q9HCU9